| Front | hemangioma1. define2. how common3. how is it found |
| Back | 1. Lesion consists of discrete red-blue hemorrhagic nodules composed of dilated (cavernous) endothelial lined blood filled channels. 2. Most common benign neoplam of liver.3. Incidental discovery |
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| Front | WILSON'S DISEASE1. define 2. diagnostic tests x33. when should it be part of the ddx4. what is on biopsy? |
| Back | 1. Autosomal recessive disorder of copper metabolism --> accumulation of toxic levels of copper in tissues (liver, brain, eye).2. ceruloplasmin levels are low24hr copper excretion increaseserum copper low3. liver dx in anyone <30yoa4. increased hepatic copper; copper stains may be negative, so quantitative liver copper can be performed on the biopsy specimen |
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| Front | HEREDITARY HEMOCHROMATOSIS1. define2. basic pathogen3. clinical presentation (TRIAD:) + 5 more4. liver biopsy and diagnosis x25. best screening test6. Tx |
| Back | 1. autosomal recessive disorder resulting in excessive intestional iron absorption2. synthesis of hepcidin is somehow decreased --> deficiency of hepcidin --> excessive intestinal Fe absorption3. cirrhosis, diabetes, skin pigmentation (so called bronze diabetes)arthralgiaslethargy hypogonadismabdominal painCHF4. cirrhosisincreased Fe confirms dx5. fasting transferrin saturation6. clear excessive iron from the tissues, using phlebotomy or iron chelating agents |
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