| Back | change in composition of microbiota in inflammatory bowel diseases, irritable colon, autism, atherosclerosis, type 2 diabetes mellitus, obesity, rheumatoid arthritissymptoms: flatulence, diarrhea, constipation, nausea, pain in abdomen, decreased appetite, unpleasant taste in moththere are 160 types of microbs in microbiome in one person:they have protective and metabolic functions:protect against other pathogenic microbes by competing with them for binding sites at mucosal barrier and help in mucosal growth, important for innate immunity via TLR acquired immunity: stimulus of CD4 T cell differentation targeting the Th1 pattern of immunitymetabolic: digestion of indigestible substances, conjugation and dehydrogenation of bile salts, regulation of endocrine functions like in stress responses, biosynthesis of vitamins like K and B12, biotransformation of xenobiotics and drugs |