| Front | What are the similarities and differences of Reis-Bucklers Corneal Dystrophy and Thiel-Behnke Corneal Dystrophy? |
| Back | ● Both are due to TGFB1 mutations ● Reis-Bucklers: autosomal dominant, painful recurrent erosions, 1st/2nd decade, affects Bowman’s layer, more common to have recurrent erosion episodes and more severe stromal scarring ● Thiel Behnke: also affects Bowman’s layer; has curly fibers on electron microscopy |
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| Front | What histologic feature is high risk for malignancy of a conjunctival pigmented lesion? |
| Back | ● Epithelioid morphology (large, hyperchromatic nuclei, prominent nucleoli, and moderate to abundant cytoplasm) and pagetoid spread (migration into the superficial epithelium) |
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| Front | What are the characteristics of acanthamoeba keratitis? |
| Back | ● Severe pain ● Range from no inflammation to marked granulomatous reaction ● Contact lens wearer with poor hygiene ● Cysts (C) and trophozoites (T) within corneal stroma |
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