Biochemistry, Metabolic Pathways

Chemistry

M

Sample Data

Text Glycolysis produces 2 cytosolic NADH but these are unable to enter into the mitochondria directly. Instead, we can reduce {{c1::oxalacetate}} to malate which can enter the mitochondria via the Malate/Aspartate Shuttle{{c2::Malate}} Dehydrogenase is found both in the cytosol and in the mitochondrial matrix In the matrix, malate can be oxidized back to oxaloacetate as part of the {{c3::citric acid cycle,}} generating mitochondrial NADH in the process.
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Text {{c1::Glut 4}} is present in adipose cells and muscle. Responds to glucose levels in peripheral blood. Insulin increases the rate of uptake by increasing the {{c2::number of receptors}} on the cell surface Km = 5, saturated at normal levels Km of other Glut is 15
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Text At Complex 2, there are three steps completed in order to move electrons to Complex 3First, succinate is oxidized to {{c1::fumerate}} and FADH2 is produced.Then, FADH2 is oxidized to FAD when the electrons are shuttled to {{c2::Fe-S centers}}Finally, {{c3::ubiquinone/Coenzyme Q}} accepts electrons from the Fe-S centers and transports them to Complex 3
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