pathology

Pathology
pathology

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Front what 2 reasons does hypertrophy and hyperplasia occur
Back -increased functional demand-stimulation by hormonescan be pathological or physiological
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Front outline the normal role of p53
Back -DNA damage > p53 binds to DNA in G1 > blocks cell cycle by activating other components eg. p21 > DNA repair can occur via transcription of other factors wuch as GADD45 > normal cell if damage is fixed, can also induce apoptosis or senescence
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Front what are the different kinds of warts
Back >SEBORRHEIC KERATOSIS (Verruche Seborroiche) (benign, well circumscribed and defined, part of normal skin aging)>VIRAL WART (Verruca) (due to HPV, human papilloma virus) with contact through microlesions into the mucosa>common wart (pre-cancerosis, cutaneous or as a papule)>keratoacanthoma shares common wart morphology except at the top of the lesion there is strong keratinisation surrounded by chronic inflammation, can undergo necrosis and produce scars>condyloma (condylomata acuminata, sexually transmitted), growth is confined and does not spread, but can induce inflamamtion and thus can be malignant
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