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| Front | state where the reduction of non-haem iron occurs and describe it |
| Back | occurs: duodenum and proximal jejnum (transported across centerocytemechanism: Dcytb (duodenal cytochrome b) reduces Fe3+ to Fe2+ at brush border then DMT1 transports Fe2+ into the enterocyte |
| Front | give the function of cytokines and growth factors in the bone marrow niche |
| Back | regulate the proliferation, survival and differentiation of hematopoietic cells |
| Front | state what haptoglobin binds to and its function |
| Back | binds: free haemobloginfunction: recognised by CD163 receptors on macrophages and complex cant pass through kidney glomeruli so it prevents iron loss and protects kidney |