it is deck regarding metabolic pathways of glucose
| Front | what is disadvantage of polyol pathway |
| Back | sorbitol formed has significant osmotic effectssince it is alcohol it is hydrophilic it attract or absorb water(osmosis) leading to tissue swelling eg cataractsturning lense from clear tanslucent to blurry and opaquethats why in diabetes it also causes polyuria since sorbitol sugar will pull water in urine occur in patient with glactosemia and dibetes but not fructosurea |
| Front | How UDP galactose formed during galactose metabolism is converted into UDP glucose back |
| Back | It is isomerized back to UDP-glucose by UDP hexose 4-epimeraseThis can also form UDP galactose from UDP- glucose too when UDP galactose is needed to form glyprotien, glycolipids |
| Front | What is pancreatitis |
| Back | In pancreatitis there is inflammation of pancreas due to drug or alcohol abuseZymogen stored in pancreas will turn active inside pancreas and start damaging pancreas wall itselfSerum amylase,lipase increase |