deck about medicinal chemistry. local anaesthetic, diabetes, penicillin, solubility, Log P
| Text | Lipophilicity - lipophilicity refers to:1) how well a drug dissolves in body fluid ({{c1::solubility}}), 2) crosses the cell mambrane ({{c1::permeability}}), 3) bind to fatty components ({{c1::distribution}}), 4) how much of the original drug is left to reach the drug target ({{c1::bioavailability}}) |
| Back Extra |
| Front | What is the equation for log P |
| Back | log p = log ([molecule]org/[molecule]aq) |
| Front | what two processes are involved in the action of l.a? |
| Back | - diffusion of drug through nerve sheath - binding at receptor site of the ion channel |