Clinical Pathology Y2 Leeds
| Text | E. coli O157:H7 InfectionProduces toxin: {{c1::Shiga-toxin}}High risk of {{c2::hemolytic uremic syndrome}} in {{c3::children <5 (10-15% cases)}}Onset: {{c4::2-5d}} post-infxPresentation: {{c5::watery → bloody diarrhea, fever, cramps, HUS (renal failure, thrombocytopenia, anemia)}}Tx for HUS against Shiga toxin 2: {{c6::Eculizumab}}Drugs to avoid: {{c7::loperamide, opioids, NSAIDs}}Infectious for how long: {{c8::48h max}} |
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