| Front | What controls if gluconeogenesis or glycolysis dominates? (2) |
| Back | Energy chargeLow ATP/ AMP ratio: glycolysisHigh ATP/ AMP ratio: glucogenesisGlucose concentrationglucose high: glycolysisglucose low: glucogenesis |
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| Front | After glycolysis and before CAC, what reaction must occur? Where does it occur? |
| Back | The conversion of pyruvate to acetyl CoA.This takes place in the matrix of the mitochondria. |
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| Front | Explain the mechanism of pyruvate carboxylase in the formation of ____: Three stages, know what it's trying to make, and know the structural part. |
| Back | Forming oxaloacetateHCO3- + ATP -> HoCo2-PO3-2 + ADPBiotin-enzyme + HOCO2-PO3-2 -> CO2-biotin-enzyme + PCO2-biotin-enzyme + pyruvate -> biotin-enzyme + oxaloacetatePyruvate carboxylase functions as a tetramer. The BC domain of one subunit catalyzes the formation of carboxyphosphate and attaches CO2 to BCCP. BCCP then leaves the biotin carboxylase active site and swings around to the CT domain, which transfers the CO2 to pyruvate to form oxaloacetate. |
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