Musculoskeletal Anatomy
Anatomy
Musculoskeletal Anatomy
Sample Data
| Text | {{c1::Endochondral Ossification}} - process by which bones below the base of the skull form - late in the second month of development this process uses hyaline cartilage “bones” formed earlier as models for bone construction. - hyaline cartilage must be {{c2::broken down}} as ossification proceeds - example: formation of long bone begins in center of hyaline cartilage shaft at a region called the {{c3::primary ossification center}} - blood vessels infiltrate the {{c4::perichondrium}} covering the hyaline cartilage “bone.” - as a result, the underlying {{c5::mesenchymal cells}} specialize into {{c5::osteoblasts}} - now ossification can begin: I. A bone collar forms around the diaphysis of the hyaline cartilage model II. Cartilage in the center of the diaphysis calcifies and then develops cavities III. The periosteal bud (nutrient artery/vein/nerve fibers) invades the internal cavities and spongy bone forms IV. The diaphysis elongates and a medullary cavity forms - secondary ossification centers appear in the epiphyses V. The epiphyses ossify - when completed, hyaline cartilage remains only in the epiphyseal plates and articular cartilages |
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