USMLE World biochemistry
Chemistry
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Sample Data
| Front | -15 y/o boy comes with unexplained erythrocytosis on lab analysis.-Father & sister also have high red cell levels.-Further analysis shows that this mutation impairs the ionic interaction between B-subunit & 2,3-bisphosphoglycerate.-As a result of this mutation, the patient's hemoglobin will be most similar to what hemoglobin types? |
| Back | Hemoglobin Fbecause the mutation causes low affinity of HbA to 2,3-BPG, which inhibit 2,3-BPG to bind to HbA, but will increase HbA affinity to oxygen. Thus will resemble HbF due to high affinity to oxygen.Normally, HbA has high affinity to 2,3 BPG. HbF has high affinity to oxygen. |
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| Front | In what reaction Xylulose will be found? |
| Back | In the pentose phosphate pathway.
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| Front | - 65 y/o woman with chronic obstructive pulmonary disease & type 2 DM.-She's hospitalized with septicemia.-Cultures shows rapidly dividing gram-negative bacteria.-Replication of theses microbial cells requires synthesis of two daughter strands of DNA using the parents strands as templates.-Which processes will differ the most between the 2 dauther strands formed at each replication fork? |
| Back | Joining of DNA fragments by ligasewhich is specific for lagging strands. |
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