Biochemistry- Fatty Acid Metabolism

Chemistry
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Front What is the first step of fatty acid synthesis? How does this occur? Relate this compound to CAC too.
Back The first step is to transfer acetyl-CoA to the cytoplasm. This is done with the help of citrate, which acts as a shuttle.The citrate that helps acetyl-CoA also inhibits PFK, which will inhibit CAC.
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Front What is the second step of synthesizing fatty acids? What is the coenzyme? What is special about this step?
Back Activation of acetyl CoA to form malonyl CoAThe coenzyme is biotin.This is the COMMITTED STEP of fatty acid synthesis.
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Front How do you regulate fatty acid synthesis? Why that enzyme?
Back allosteric regulation of acetyl CoA carboxylase phosphorylation of acetyl CoA carboxylase?acetyl CoA carboxylase is the committed step of the reaction.
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