| Back | A mutation that affects large segments of chromosomes, leading to structural changes. Subtypes include:Deletion – A section of a chromosome is lost.Inversion – A section breaks off, flips, and reattaches.Duplication – A section is copied more than once, altering protein production.Translocation – A section breaks off and attaches to another chromosome (similar to crossing over, but occurs by mistake between unrelated, non-homologous chromosomes and can cause genetic disorders)Non-disjunction – Chromosomes fail to separate properly during meiosis, leading to an abnormal number of chromosomes |