Cell Biology Chapter 7: Aerobic Respiration
| Front | Know how ATP synthase converts the proton gradient into ATP production. What is the model for how it makes and releases ATP? Understand how movement of protons through the enzyme relates to changes in binding affinity for substrates and products – the “binding change mechanism of energy coupling”. Understand the O, L, and T conformation and how this relates to ATP production. |
| Back | Binding change mechanism: Protons move down gradient (Fo)C-ring rotor and central gamma shaft rotatesBeta subunits change shape |
| Front | What is the final electron acceptor? What happens if this molecule is unavailable? What happens to this molecule after it is reduced? |
| Back | OxygenATP cannot be made |
| Front | Know the four main complexes of the electron transport chain. At what points in the electron transport chain are electrons introduced? What “happens” as electrons are passed down the electron transport chain? Be able to trace the path of an electron through the chain starting from NADH or FADH2. What “mobile” molecules transfer the electrons between the different complexes? |
| Back | Complex 1: NADH dehydrogenaseAccepts e- from NADH transfers to UbComplex 2: Succinate dehydrogenaseAccepts electrons from FADH₂ (from succinate) → transfers to CoQComplex 3: Cyt cTransfers electrons from Ub → cytochrome cComplex 4: Cyt cTransfers electrons from cytochrome c → O₂ (forming H₂O) |