Anatomic Pathology Board Study (AP-Part2)
Pathology
This is to prepare for the American Board of Pathology: Anatomic Pathology Examination.
The AP deck was split into two parts since the files were large (this is Part 2).
The images are from various references including Pathology Outline, ExpertPath, and Osler 2021.
Sample Data
| Text | Both located in spinal cord/Cauda Equina:Left: {{c1::Myxopapillary ependymoma}}Right: {{c1::Paraganglioma}}
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| Text | A 45 year old female with a history of smoking presents with a two week history of a lump in the throat. Physical exam reveals a 2 cm yellow tan mass at the base of the tongue. Histology of the biopsy is shown. Which of the following is the lesion and follow up?{{c1::Malakoplakia. It consists predominantly of macrophages, with acute and chronic inflammation. The collection of large histiocytes with granular eosinophilic cytoplasm are called von Hansemann cells. Michaelis-Gutmann bodies are present within and outside the macrophages - look for the gray round targetoid inclusions. In the head and neck, malakoplakia is most often caused by Rhodococcus equi, and in the urinary tract it is most often caused by E. coli (> Proteus). It should be treated with antibiotics.}}
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| Extra | DDx: Granular cell tumor is believed to be derived from Schwann cells. Granular cell tumor inclusions are large eosinophilic intracytoplasmic granules surrounded by a clear halo, called pustulo-ovoid bodies.
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| Text | Histological appearance of pheochromocytomaHow do you define malignancy?{{c1::• Zellballen pattern• Vascular net work• Cellular/nuclear pleomorphism is often present• Mitotic figures are rare.• Malignancy is based exclusively on the presence of metastases.
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