8/22 - DB
| Front | normal cell + severe stress + irreversible cell injury --> |
| Back | cell death |
| Front | formation of fatty steak |
| Back | - types of intracellular accumulation- macrophages in blood vessels uptake cholesterol in excess (and stays inside macrophages) - cholesterol-filled macrophages accumulate in blood vessels and narrows them |
| Front | types of cell injury |
| Back | - decrease in ATP- mitochondrial damage- entry of Ca2+ - increase in ROS- membrane damage - protein misfolding, DNA damage |